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Australia's Research Peptide Specialists
Research Compounds
Precision formulated research peptides designed for purity, consistency, and performance.
99%+
Purity
GMP
Certified
25+
Compounds
4.94★
Avg Rating
Showing 12 compounds
Research Use Only
Best Seller
In Stock
Weight Management
RETA
Triple agonist peptide studied for metabolic regulation and adipose tissue research.
★★★★☆4.9 (47)
$149AUD
Research Use Only99%+ Purity
In Stock
Weight Management
Tirzepatide
Dual GIP/GLP-1 receptor agonist researched for glucose and energy metabolism.
★★★★☆4.8 (33)
$129AUD
Research Use Only99%+ Purity
In Stock
Weight Management
Semaglutide
GLP-1 receptor agonist with extended half-life for metabolic and appetite research.
★★★★☆4.9 (58)
$99AUD
Research Use Only99%+ Purity
In Stock
Recovery
BPC-157
Body Protective Compound studied for tissue repair and angiogenesis in preclinical models.
★★★★☆4.9 (72)
$79AUD
Research Use Only99%+ Purity
In Stock
Recovery
TB-500
Thymosin Beta-4 analogue researched for cell migration and wound healing acceleration.
★★★★☆4.8 (41)
$89AUD
Research Use Only99%+ Purity
Popular
In Stock
Recovery
GLOW Blend
GHK-Cu, BPC-157, TB-500 synergistic blend for aesthetics and tissue research.
★★★★★5.0 (29)
$159AUD
Research Use Only99%+ Purity
In Stock
Performance
CJC-1295 + Ipamorelin
GHRH analogue combined with ghrelin receptor agonist for growth hormone release research.
★★★★☆4.8 (36)
$139AUD
Research Use Only99%+ Purity
In Stock
Performance
IGF-1 LR3
Long-Arg3 IGF-1 analogue with extended bioavailability for cellular proliferation research.
★★★★☆4.7 (24)
$89AUD
Research Use Only99%+ Purity
Low Stock
Performance
Tesamorelin
Synthetic GHRH analogue studied for visceral adiposity and growth hormone axis modulation.
★★★★☆4.8 (18)
$119AUD
Research Use Only99%+ Purity
In Stock
Wellness
DSIP
Delta Sleep-Inducing Peptide researched for sleep architecture and neuroendocrine signalling.
★★★★☆4.7 (21)
$69AUD
Research Use Only99%+ Purity
In Stock
Wellness
PT-141
Melanocortin receptor agonist studied for CNS-mediated signalling pathways in research.
★★★★☆4.8 (31)
$99AUD
Research Use Only99%+ Purity
In Stock
Wellness
MOTS-c
Mitochondrial-derived peptide for cellular energy regulation and metabolic homeostasis research.
★★★★☆4.9 (27)
$129AUD
Research Use Only99%+ Purity
Research Use Only. All CoreLabs products are intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA, FDA, or any regulatory body for human consumption or therapeutic use.
DISCLAIMER: All products intended solely for in vitro research. Not for human consumption.
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All products sold by CoreLabs are for in vitro research purposes only. Not approved by TGA or FDA for human use.
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✓ GMP Certified
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Usage Notes
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For in vitro research use only. Reconstitute with bacteriostatic water. Store lyophilized at -20°C. Once reconstituted, refrigerate at 2-8°C and use within 30 days. Avoid freeze-thaw cycles.
CoreLabs was founded to bring pharmaceutical-grade research compounds to Australian researchers. Every batch we release has been independently verified before it leaves our warehouse.
Our compounds are manufactured in GMP-certified facilities using the highest quality raw materials. Every product ships with a Certificate of Analysis confirming purity and batch number.
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25+
Research Compounds
4.94
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From Lab to Your Door
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Last updated: January 2026
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Refund Policy
Last updated: January 2026
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We accept returns only for damaged, defective, or incorrectly sent items. All return requests must be made within 7 days of delivery.
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Contact info@corelabsofficial.com with your order number and photos. We will arrange a replacement or refund at no cost.
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Terms of Service
Last updated: January 2026
Research Use Only
All products are strictly for in vitro scientific research by qualified professionals. By purchasing you confirm products will be used exclusively for lawful research purposes.
Regulatory Compliance
CoreLabs products are not approved by the TGA, FDA, or any regulatory body for human or animal therapeutic use. It is the purchaser's responsibility to comply with all applicable laws.
Age Requirement
You must be 18 years or older to purchase from CoreLabs.
Limitation of Liability
CoreLabs accepts no liability for any misuse of products beyond their intended laboratory research purpose.
Governing Law
These terms are governed by the laws of New South Wales, Australia.
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Shipping Policy
Last updated: January 2026
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Packaging
All orders dispatched in plain, unmarked outer packaging with no CoreLabs branding visible on the outside.
Tracking
All orders include tracking. Your tracking number will be emailed once dispatched. Use our Track Order page.
Home › RETA (Retatrutide)
Triple Receptor Agonist — GLP-1 / GIP / Glucagon
RETA (Retatrutide)
★★★★★4.9(47 reviews)
$149AUD
Retatrutide (LY3437943) is a novel triple agonist that simultaneously activates GLP-1, GIP, and glucagon receptors. Developed by Eli Lilly, it is currently in Phase III clinical trials. Phase II data showed average body weight reductions of 17.5% at 24 weeks and 24.4% at 48 weeks — results that surpass dual agonists like tirzepatide in head-to-head preclinical comparisons.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
Retatrutide (LY3437943) is a novel triple agonist that simultaneously activates GLP-1, GIP, and glucagon receptors. Developed by Eli Lilly, it is currently in Phase III clinical trials. Phase II data showed average body weight reductions of 17.5% at 24 weeks and 24.4% at 48 weeks — results that surpass dual agonists like tirzepatide in head-to-head preclinical comparisons.
Retatrutide activates three key metabolic hormone receptors simultaneously: GLP-1R (reduces appetite, delays gastric emptying, increases insulin secretion), GIPR (enhances glucose-dependent insulin release, improves lipid metabolism), and GCGR (increases energy expenditure, promotes lipolysis in adipose tissue). This triple synergy produces superior metabolic effects compared to single or dual agonists.
Phase 2 trials (NEJM, 2023) demonstrated dose-dependent weight loss up to 24.2% at 48 weeks with the 12mg dose. A 2024 Nature Medicine study confirmed 86% reduction in liver fat content in subjects with metabolic-associated steatotic liver disease. Phase III TRIUMPH trials are currently ongoing.
Form
Lyophilized powder
CAS Number
2381272-12-2
Molecular Weight
4731.5 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted with bacteriostatic water, refrigerate at 2–8°C and use within 28 days.
Sequence
Modified GIP analogue with C18 fatty acid chain
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › Tirzepatide
Dual Receptor Agonist — GLP-1 / GIP
Tirzepatide
★★★★★4.8(33 reviews)
$129AUD
Tirzepatide is a dual GIP and GLP-1 receptor agonist developed by Eli Lilly (brand name Mounjaro/Zepbound). It is FDA-approved for type 2 diabetes and obesity management. As a research compound, it is studied for its profound effects on metabolic parameters, glycaemic control, and adipose tissue regulation.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
Tirzepatide is a dual GIP and GLP-1 receptor agonist developed by Eli Lilly (brand name Mounjaro/Zepbound). It is FDA-approved for type 2 diabetes and obesity management. As a research compound, it is studied for its profound effects on metabolic parameters, glycaemic control, and adipose tissue regulation.
Acts as a single molecule with activity at both GIP and GLP-1 receptors. GLP-1 receptor agonism suppresses appetite via hypothalamic signalling and delays gastric emptying. GIP receptor agonism enhances insulin secretion, improves beta-cell function, and modulates lipid metabolism. Together, these pathways produce synergistic reductions in food intake and energy balance.
SURMOUNT-1 trial (NEJM, 2022): 20.9% average body weight reduction at 72 weeks with 15mg dose. SURPASS trials demonstrated superior HbA1c reduction vs semaglutide. Studies also show significant reductions in visceral adipose tissue, blood pressure, and lipid profiles.
Form
Lyophilized powder
CAS Number
2023788-19-2
Molecular Weight
4813.6 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 28 days.
Sequence
GIP/GLP-1 dual agonist with C20 fatty acid modification
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › Semaglutide
GLP-1 Receptor Agonist
Semaglutide
★★★★★4.9(58 reviews)
$99AUD
Semaglutide is a long-acting GLP-1 receptor agonist (brand names: Ozempic, Wegovy) with a half-life of approximately 7 days due to its albumin-binding fatty acid modification. It is one of the most extensively studied metabolic peptides, with multiple large Phase 3 trials confirming its efficacy in weight management and glycaemic control research.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
Semaglutide is a long-acting GLP-1 receptor agonist (brand names: Ozempic, Wegovy) with a half-life of approximately 7 days due to its albumin-binding fatty acid modification. It is one of the most extensively studied metabolic peptides, with multiple large Phase 3 trials confirming its efficacy in weight management and glycaemic control research.
Semaglutide mimics endogenous GLP-1 by binding to GLP-1 receptors in the pancreas, hypothalamus, and brainstem. It stimulates glucose-dependent insulin secretion, suppresses glucagon, delays gastric emptying, and reduces appetite via central nervous system pathways. Its modified structure resists DPP-4 degradation and binds albumin, extending its half-life to ~168 hours.
STEP 1 trial (NEJM, 2021): 14.9% average body weight reduction at 68 weeks with 2.4mg weekly. SUSTAIN trials: consistent HbA1c reductions of 1.5–1.8%. SELECT trial (2023) demonstrated 20% reduction in major cardiovascular events in subjects with overweight/obesity.
Form
Lyophilized powder
CAS Number
910463-68-2
Molecular Weight
4113.6 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 28 days.
Sequence
34 amino acid GLP-1 analogue with C18 fatty diacid modification
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › BPC-157
Body Protective Compound — 15 Amino Acid Peptide
BPC-157
★★★★★4.9(72 reviews)
$79AUD
BPC-157 (Body Protective Compound-157) is a 15 amino acid peptide derived from a partial sequence of human gastric juice protein BPC. It has been studied extensively in preclinical models for its effects on tissue repair, angiogenesis, and cytoprotection across a diverse range of tissues including tendon, ligament, muscle, bone, and the gastrointestinal tract.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
BPC-157 (Body Protective Compound-157) is a 15 amino acid peptide derived from a partial sequence of human gastric juice protein BPC. It has been studied extensively in preclinical models for its effects on tissue repair, angiogenesis, and cytoprotection across a diverse range of tissues including tendon, ligament, muscle, bone, and the gastrointestinal tract.
BPC-157 promotes angiogenesis via upregulation of VEGF and eNOS signalling, activates the FAK-paxillin pathway to enhance cellular migration, modulates the dopaminergic and serotonergic systems centrally, and demonstrates anti-inflammatory effects through NF-κB inhibition. It also activates the Akt/mTOR pathway, supporting cellular survival and proliferation.
Hundreds of preclinical studies (rats, mice) demonstrate accelerated healing of tendons, ligaments, muscle tears, and bone fractures. Studies show gastroprotective effects against NSAID-induced damage, cytoprotection of intestinal epithelium, and neuroprotective effects. No completed human clinical trials as of 2025; research remains at preclinical stage.
Form
Lyophilized powder
CAS Number
137525-51-0
Molecular Weight
1419.5 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 30 days.
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
TB-500 is a synthetic analogue of the 43 amino acid naturally occurring peptide Thymosin Beta-4 (Tβ4), specifically the active fragment Ac-SDKP. It is found in virtually all human cells and tissues. TB-500 is primarily studied for its role in actin sequestration, cell migration, angiogenesis, and wound healing — processes central to tissue repair across multiple organ systems.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
TB-500 is a synthetic analogue of the 43 amino acid naturally occurring peptide Thymosin Beta-4 (Tβ4), specifically the active fragment Ac-SDKP. It is found in virtually all human cells and tissues. TB-500 is primarily studied for its role in actin sequestration, cell migration, angiogenesis, and wound healing — processes central to tissue repair across multiple organ systems.
TB-500 binds G-actin monomers, preventing their polymerisation into F-actin filaments. This promotes cell motility and migration by regulating the actin cytoskeleton. It also upregulates integrin expression, stimulates angiogenesis via VEGF pathways, and demonstrates anti-inflammatory properties through downregulation of pro-inflammatory cytokines (IL-1β, TNF-α).
Preclinical studies show accelerated healing of dermal wounds, cardiac muscle, corneal injuries, and tendon/ligament damage. A notable study demonstrated Tβ4's role in cardiac stem cell mobilisation after myocardial infarction in mice. Often studied in combination with BPC-157 for synergistic tissue repair effects.
Form
Lyophilized powder
CAS Number
77591-33-4
Molecular Weight
4963.5 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 30 days.
Sequence
Ac-Ser-Asp-Lys-Pro (active LKKTET fragment)
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › GLOW Blend (GHK-Cu + BPC-157 + TB-500)
Synergistic Tissue Repair & Aesthetic Research Blend
GLOW Blend (GHK-Cu + BPC-157 + TB-500)
★★★★★5.0(29 reviews)
$159AUD
The GLOW Blend combines three extensively researched peptides — GHK-Cu (copper tripeptide), BPC-157, and TB-500 — in a single lyophilized formulation. Each compound addresses distinct but complementary mechanisms in tissue regeneration, making this stack popular in aesthetic and recovery-focused research protocols.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
The GLOW Blend combines three extensively researched peptides — GHK-Cu (copper tripeptide), BPC-157, and TB-500 — in a single lyophilized formulation. Each compound addresses distinct but complementary mechanisms in tissue regeneration, making this stack popular in aesthetic and recovery-focused research protocols.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Cu²⁺) is a naturally occurring copper-binding tripeptide that stimulates collagen synthesis, activates metalloproteinases for ECM remodelling, and promotes dermal fibroblast proliferation. Combined with BPC-157 (angiogenesis, anti-inflammatory) and TB-500 (cell migration, actin remodelling), the blend addresses multiple pathways in wound healing, skin repair, and tissue regeneration simultaneously.
GHK-Cu is among the most studied cosmetic peptides, with research confirming its ability to upregulate collagen I, III, elastin, and fibronectin expression. It has also demonstrated gene expression effects on over 4,000 human genes. The combination of all three compounds has been studied for synergistic wound healing in preclinical models.
Form
Lyophilized powder blend
CAS Number
89030-95-5 (GHK-Cu)
Molecular Weight
Blend formulation
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 28 days.
Sequence
GHK-Cu: Gly-His-Lys-Cu²⁺ | BPC-157: 15AA fragment | TB-500: Ac-SDKP fragment
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › CJC-1295 + Ipamorelin
GHRH Analogue + Ghrelin Receptor Agonist Blend
CJC-1295 + Ipamorelin
★★★★★4.8(36 reviews)
$139AUD
CJC-1295 is a modified GHRH analogue with a Drug Affinity Complex (DAC) modification that extends its half-life to approximately 7–8 days. Ipamorelin is a highly selective ghrelin receptor agonist (GHRP) with minimal off-target effects. When combined, they stimulate GH secretion through two distinct and complementary pathways, producing a synergistic pulsatile GH release.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
CJC-1295 is a modified GHRH analogue with a Drug Affinity Complex (DAC) modification that extends its half-life to approximately 7–8 days. Ipamorelin is a highly selective ghrelin receptor agonist (GHRP) with minimal off-target effects. When combined, they stimulate GH secretion through two distinct and complementary pathways, producing a synergistic pulsatile GH release.
CJC-1295 acts at GHRH receptors in the anterior pituitary, amplifying the natural growth hormone release pulse. Ipamorelin acts at ghrelin receptors (GHS-R1a), independently stimulating GH secretion without significantly affecting cortisol or prolactin — a key advantage over older GHRPs like GHRP-6. Together, they amplify both the frequency and amplitude of GH pulses, leading to downstream IGF-1 elevation.
A 2006 study (J Clin Endocrinol Metab) confirmed CJC-1295 produced sustained increases in plasma GH and IGF-1 levels lasting 14 days after a single injection. Ipamorelin research confirms selective GH release with a favourable safety profile. The combination is widely studied in the context of body composition, recovery, and age-related GH decline research.
Form
Lyophilized powder blend
CAS Number
863288-34-0 (CJC-1295) | 170851-70-4 (Ipamorelin)
Molecular Weight
3368.0 Da (CJC-1295) | 711.9 Da (Ipamorelin)
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 28 days.
Sequence
CJC-1295: Modified 30AA GHRH fragment + DAC | Ipamorelin: Aib-His-D-2Nal-D-Phe-Lys-NH₂
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › IGF-1 LR3
Long-Arg3 Insulin-Like Growth Factor-1 Analogue
IGF-1 LR3
★★★★★4.7(24 reviews)
$89AUD
IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a modified analogue of endogenous IGF-1, with a 13 amino acid N-terminal extension and a substitution of glutamic acid for arginine at position 3. These modifications reduce its binding affinity for IGF binding proteins (IGFBPs) by approximately 1000-fold, dramatically extending its effective half-life from ~10 minutes to approximately 20–30 hours.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a modified analogue of endogenous IGF-1, with a 13 amino acid N-terminal extension and a substitution of glutamic acid for arginine at position 3. These modifications reduce its binding affinity for IGF binding proteins (IGFBPs) by approximately 1000-fold, dramatically extending its effective half-life from ~10 minutes to approximately 20–30 hours.
IGF-1 LR3 binds to the IGF-1 receptor (IGF-1R), activating PI3K/Akt and MAPK/ERK signalling cascades. This promotes cellular proliferation, protein synthesis, glucose uptake, and inhibition of apoptosis. Due to reduced IGFBP binding, a greater proportion of LR3 remains in bioavailable form compared to native IGF-1, enhancing its potency in research models.
Widely used in cell culture research as a media supplement to promote cell growth and differentiation. In vivo studies demonstrate significant effects on skeletal muscle hypertrophy, satellite cell activation, and nitrogen retention. IGF-1 signalling pathways are extensively studied in the context of sarcopenia, wound healing, and metabolic research.
Form
Lyophilized powder
CAS Number
946870-92-4
Molecular Weight
9117.6 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Reconstitute in 0.1% acetic acid. Once reconstituted, refrigerate at 2–8°C and use within 14 days.
Sequence
83 amino acid modified IGF-1 with N-terminal extension and R3 substitution
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › Tesamorelin
Synthetic GHRH Analogue — 44 Amino Acids
Tesamorelin
★★★★★4.8(18 reviews)
$119AUD
Tesamorelin is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH), consisting of the full 44 amino acid sequence of GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus that enhances stability. It is FDA-approved under the brand name Egrifta for HIV-associated lipodystrophy, making it one of the few research peptides with regulatory approval for a specific indication.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
Tesamorelin is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH), consisting of the full 44 amino acid sequence of GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus that enhances stability. It is FDA-approved under the brand name Egrifta for HIV-associated lipodystrophy, making it one of the few research peptides with regulatory approval for a specific indication.
Tesamorelin binds to and activates GHRH receptors in the anterior pituitary gland, stimulating the synthesis and pulsatile release of growth hormone. This leads to downstream elevation of IGF-1 via hepatic stimulation. Unlike exogenous GH administration, tesamorelin preserves the pulsatile nature of GH secretion, which is important for maintaining physiological feedback mechanisms.
Phase 3 trials in HIV-associated lipodystrophy demonstrated 15–18% reduction in visceral adipose tissue after 26 weeks. Studies also show improvements in triglycerides, cognition, and body composition. Research in non-HIV populations has examined effects on visceral fat, GH deficiency, and metabolic parameters.
Form
Lyophilized powder
CAS Number
218949-48-5
Molecular Weight
5135.9 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 21 days.
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › DSIP (Delta Sleep-Inducing Peptide)
Endogenous Neuropeptide — Sleep & Neuroendocrine Research
DSIP (Delta Sleep-Inducing Peptide)
★★★★★4.7(21 reviews)
$69AUD
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring 9 amino acid neuropeptide first isolated from rabbit cerebral venous blood in 1977. It is found in the hypothalamus, limbic system, pituitary, and various peripheral tissues. DSIP is studied for its complex effects on sleep architecture, neuroendocrine regulation, and stress response modulation.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring 9 amino acid neuropeptide first isolated from rabbit cerebral venous blood in 1977. It is found in the hypothalamus, limbic system, pituitary, and various peripheral tissues. DSIP is studied for its complex effects on sleep architecture, neuroendocrine regulation, and stress response modulation.
DSIP modulates delta wave (slow wave) sleep by acting on specific brain regions including the hypothalamus and limbic system. It influences the release of multiple pituitary hormones including GH, LH, and corticotropin. DSIP also demonstrates antioxidant properties, modulates the HPA axis stress response, and has been studied for its effects on circadian rhythm regulation.
Originally described in Monnier et al. (1977). Subsequent research identified DSIP in multiple tissues and confirmed neuroendocrine regulatory effects. Studies show potential effects on stress-induced hormone dysregulation, sleep quality parameters, and antioxidant defence. Research is ongoing regarding its role in the sleep-wake cycle at the molecular level.
Form
Lyophilized powder
CAS Number
62568-57-4
Molecular Weight
850.9 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 30 days.
Sequence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › PT-141 (Bremelanotide)
Melanocortin Receptor Agonist — CNS Signalling Research
PT-141 (Bremelanotide)
★★★★★4.8(31 reviews)
$99AUD
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide and an analogue of alpha-MSH (alpha-melanocyte-stimulating hormone). It acts as a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R). PT-141 is FDA-approved under the brand name Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women, making it one of few peptides with regulatory approval.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide and an analogue of alpha-MSH (alpha-melanocyte-stimulating hormone). It acts as a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R). PT-141 is FDA-approved under the brand name Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women, making it one of few peptides with regulatory approval.
PT-141 acts centrally via melanocortin 3 and 4 receptors (MC3R/MC4R) in the hypothalamus and limbic system, activating neural pathways involved in sexual arousal and motivation — distinct from PDE5 inhibitors which act peripherally. MC4R activation in the paraventricular nucleus of the hypothalamus is believed to be the primary mechanism underlying its CNS-mediated effects.
Phase 2 and 3 clinical trials confirmed efficacy for HSDD leading to FDA approval in 2019. Research also examines MC receptor involvement in energy homeostasis, inflammation, and neuroprotection. Studies demonstrate effects independent of the vascular system, making it a useful tool for CNS melanocortin pathway research.
Form
Lyophilized powder
CAS Number
189691-06-3
Molecular Weight
1025.2 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 30 days.
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
Home › MOTS-c
Mitochondrial-Derived Peptide — Metabolic Homeostasis Research
MOTS-c
★★★★★4.9(27 reviews)
$129AUD
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16 amino acid peptide encoded within the mitochondrial genome — specifically the 12S ribosomal RNA gene. Discovered by Lee et al. at USC in 2015, it represents a novel class of mitochondria-derived peptides (MDPs) that act as retrograde signals from mitochondria to the nucleus and other cellular compartments, regulating metabolic homeostasis.
✓ GMP Certified
✓ 99%+ Purity
✓ HPLC Tested
✓ Third-Party Verified
Overview
Mechanism
Research
Specs
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16 amino acid peptide encoded within the mitochondrial genome — specifically the 12S ribosomal RNA gene. Discovered by Lee et al. at USC in 2015, it represents a novel class of mitochondria-derived peptides (MDPs) that act as retrograde signals from mitochondria to the nucleus and other cellular compartments, regulating metabolic homeostasis.
MOTS-c activates the AMPK pathway, which functions as a cellular energy sensor, promoting glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. It translocates to the nucleus in response to metabolic stress, where it regulates adaptive gene expression. Studies also show MOTS-c modulates the folate cycle and one-carbon metabolism, AICAR production, and purine biosynthesis.
Discovery paper (Cell Metabolism, 2015): MOTS-c treatment improved insulin sensitivity and prevented diet-induced obesity in mice. Subsequent studies show exercise-induced MOTS-c elevation. Research in ageing models demonstrates MOTS-c's role in longevity pathways. A 2021 study showed MOTS-c levels decline with age in humans, correlating with metabolic health markers.
Form
Lyophilized powder
CAS Number
1900429-84-6
Molecular Weight
2173.6 Da
Purity
≥99% (HPLC)
Storage
Store lyophilized at -20°C. Once reconstituted, refrigerate at 2–8°C and use within 28 days.
Research Use Only. This product is intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA or FDA for human consumption or therapeutic use.
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★★★★☆4.9 (27)
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Research Use Only. All CoreLabs products are intended exclusively for in vitro scientific research by qualified professionals. Not approved by the TGA, FDA, or any regulatory body for human consumption or therapeutic use.
Home › Certificate of Analysis
Certificate of Analysis
Independent third-party purity verification for every CoreLabs batch.
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Independent Third-Party Testing
Every CoreLabs batch is tested by accredited independent laboratories before release. Our Certificates of Analysis confirm purity via HPLC chromatography and molecular identity via mass spectrometry.
✓ HPLC Chromatography✓ Mass Spectrometry✓ 99%+ Purity Minimum✓ Batch-Specific Results
99%+
Min. Purity
12
Compounds
3rd
Party Tested
GMP
Certified Mfg
🧪
RETA
Triple GIP/GLP-1/Glucagon Agonist · 10mg / 20mg · 4731.5 Da
Delta Sleep-Inducing Peptide · 5mg / 10mg · 850.9 Da
99.4%
Purity
62568-57-4
CAS Number
✓ HPLC Verified
🧪
PT-141
Melanocortin Receptor Agonist · 10mg · 1025.2 Da
99.2%
Purity
189691-06-3
CAS Number
✓ HPLC Verified
🧪
MOTS-c
Mitochondrial-Derived Peptide · 10mg / 20mg · 2173.6 Da
99.1%
Purity
1900429-84-6
CAS Number
✓ HPLC Verified
Research Use Only
All CoreLabs products are supplied strictly for in vitro scientific research by qualified professionals. Not approved by the TGA, FDA, or any regulatory authority for human or veterinary therapeutic use. COA results reflect the specific batch tested and are provided for research verification purposes only.
